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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Alcohol Clin Exp Res. 2014 Sep 25;38(10):2550–2560. doi: 10.1111/acer.12527

Table 1.

List of TRPV1 SNPs included in the analysis. P values are generated via ANOVA. The reported p values are unadjusted.

Reported p-values

AUC ratings:
Receptor chr. SNP ID call rate HWE
p-value
maj/min
allele
MAF SNP
location
EtOH
WM
Burn Bitter
TRPV1 17 rs4790521 97.9% 0.71 T/C 0.37 3' UTR 0.35 0.19 0.0033
TRPV1 17 rs4790522 98.9% 0.95 C/A 0.42 3' UTR 0.12 0.79 0.50
TRPV1 17 rs224547 98.9% 0.57 A/G 0.43 Intronic 0.07 0.054 0.0044
TRPV1 17 rs4790151 98.9% 1.0 G/A 0.3 Intronic 0.16 0.84 0.35
TRPV1 17 rs161364 98.9% 0.39 C/T 0.3 Intronic 0.63 0.0021 0.30
TRPV1 17 rs8065080 96.8% 0.96 T/C 0.37 Ile585Val 0.17 0.70 0.43
TRPV1 17 rs150908 95.7% 0.07 G/A 0.35 Intronic 0.80 0.53 0.33
TRPV1 17 rs224534 98.9% 0.56 G/A 0.37 Thr469Ile 0.17 0.94 0.49
TRPV1 17 rs222747 96.8% 0.56 C/G 0.28 Met315Ile 0.48 0.78 0.74
TRPV1 17 rs150846 96.8% 1.0 C/T 0.39 Intronic 0.22 0.86 0.55
TRPV1 17 rs161386 98.9% 0.59 C/T 0.38 Intronic 0.88 0.62 0.23
TRPV1 17 rs7217945 98.9% 0.28 G/A 0.28 Intronic 0.83 0.06 0.27
TRPV1 17 rs17707155 98.9% 0.58 C/T 0.26 Intronic 0.78 0.91 0.39

TAS2R13 12 rs1015443 98.5% 0.28 C/T 0.35 Ser259Asn 0.04 0.98 0.36
TAS2R38 7 rs713598 98.4% 0.37 G/C 0.49 Ala49Pro 0.32 0.87 0.0048
TAS2R38 7 rs1726866 97.7% 0.53 C/T 0.50 Val262Ala 0.86 0.57 0.21
TAS2R38 7 rs10246939 98.5% 0.73 C/T 0.48 Ile296Val 0.87 0.68 0.055

MAF, minor allele frequency; HWE, Hardy-Weinberg equilibrium; EtOH WM, ethanol whole mouth sample 16%v/v.