Diameter and zeta potential of the siRNA-αCD22 Ab-nanocomplexes. A532-labelled SPIO NPs were combined with siRNAs and αCD22 Abs. The size and zeta potential of the nanocomplexes changed after combining the siRNAs and αCD22 Abs. Average diameter or zeta potential of SPIO NPs + A532 and SPIO NPs + A532 + siRNA + CD22 is indicated in the left upper corner of each graph.
A532, Alexa Fluor 532; αCD22 Ab, anti-CD22 antibody; SPIO, superparamagnetic iron oxide; NP, nanoparticle; siRNA, small interfering RNA.