Table 4.
Association of rs2453021 and risk for CAD or MI.
| Odds ratio (95% CI) | P | |
|---|---|---|
| All | 1.013 (0.933–1.100) | 0.757 |
| Women only | 1.019 (0.880–1.180) | 0.798 |
| Men only | 1.011 (0.920–1.113) | 0.814 |
| MI | 1.028 (0.945–1.119) | 0.521 |
| CAD only | 1.013 (0.877–1.169) | 0.862 |
The minor T allele of rs2453021 is not associated with increased risk for CAD or MI. A total of 13,029 individuals in the PROCARDIS cohort including WTCCC controls (5,765 cases and 7,264 controls) were investigated for association between rs2453021 and risk for CAD or MI. All results were adjusted for age, sex, country and relatedness. The T allele frequency was 0.394.