Table 1.
Participant characteristics
Diagnosis of osteoarthritis | No diagnosis of osteoarthritis | P -value 1 | |
---|---|---|---|
(n = 19) | (n = 141) | ||
Age, years | 59.2 (7.6) | 66.8 (7.3) | <0.0012 |
Gender, % female | 57.9 | 55.6 | 0.85 |
Body mass index, kg/m−2 | 27.2 (4.8) | 27.6 (4.8) | 0.742 |
Kellgren-Lawrence grade | |||
2 | 12 (63) | ||
3 | 6 (32) | ||
4 | 1 (5) | ||
Hip structures on magnetic resonance imaging | |||
Femoral head cartilage volume, mm3 | 1763 (321) | 3343 (808) | <0.0012 |
Femoral head bone area, mm2 | 1651 (305) | 1610 (255) | 0.582 |
Cartilage defects, number (%) | |||
Femoral head | |||
Central superolateral | 17 (89.5) | 45 (31.9) | <0.001 |
Central inferomedial | 10 (52.6) | 67 (47.5) | 0.68 |
Anterior | 12 (63.2) | 5 (3.5) | <0.001 |
Posterior | 14 (73.7) | 25 (17.6) | <0.001 |
Acetabular | |||
Central superolateral | 17 (89.5) | 37 (26.2) | <0.001 |
Anterior | 18 (94.7) | 26 (18.3) | <0.001 |
Posterior | 15 (78.9) | 50 (35.2) | <0.001 |
Femoroacetabular | |||
Central superolateral | 18 (94.7) | 64 (45.1) | <0.001 |
Anterior | 18 (94.7) | 27 (19) | <0.001 |
Posterior | 16 (84.2) | 57 (40.1) | <0.001 |
Bone marrow lesions, number (%) | |||
Femoral head | |||
Central superolateral | 10 (52.6) | 7 (5.0) | <0.001 |
Central inferomedial | 6 (31.6) | 6 (4.3) | <0.01 |
Anterior | 7 (36.8) | 2 (2.1) | <0.001 |
Posterior | 5 (26.3) | 4 (2.8) | <0.001 |
Acetabular | |||
Central superolateral | 13 (68.4) | 22 (15.6) | <0.001 |
Central inferomedial | 2 (10.5) | 3 (2.1) | 0.05 |
Anterior | 13 (68.4) | 28 (19.7) | <0.001 |
Posterior | 11 (57.9) | 18 (12.7) | <0.001 |
Femoroacetabular | |||
Central superolateral | 14 (73.7) | 27 (19.0) | <0.001 |
Central inferomedial | 6 (31.6) | 8 (5.6) | <0.001 |
Anterior | 14 (73.7) | 29 (20.4) | <0.001 |
Posterior | 13 (68.4) | 20 (14.1) | <0.001 |
Results displayed as mean (±SD) unless otherwise stated. All central regions results are the combined prevalence of regions 1 and 2. 1 P-value for differences between groups (chi-square test unless otherwise stated). 2Independent samples t-test.