Skip to main content
. Author manuscript; available in PMC: 2015 Oct 24.
Published in final edited form as: Circ Res. 2014 Oct 24;115(10):821–823. doi: 10.1161/CIRCRESAHA.114.305243

Figure 1. Genetic Etiology of Congenital Heart Disease (CHD): “The glass is half empty”3.

Figure 1

The known genetic etiology of CHD, namely chromosomal aneuploidy, rare familial CHD with Mendelian patterns of inheritance, mutations affecting proteins involved in histone modifiers (epigenetics) and Copy Number Variants (CNVs) contribute to minority of the CHD cases. The genetic etiology of CHD in the majority of the cases is unknown.