Skip to main content
. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Nurs Res. 2014 Nov-Dec;63(6):426–434. doi: 10.1097/NNR.0000000000000061

TABLE 2.

Cell Surface Markers of Activation

Leukocyte
lineage		 Markers Protein/function
Lymphoid CD62L L-selectin
CD44 Receptor for hyaluronic acid
CD25 IL-2 low affinity receptor
CD69 Type II membrane protein, C-Lectin family
CD71 Transferrin receptor protein
Myeloid CD11b Integrin
CD64a Fc receptor IgG high affinity
CD80 CD28 and CTLA4 receptor, CD86 tandem
CD86 CD28 and CTLA4 receptor, CD80 tandem
HLA-DR MHC Class II receptor
PD-1La B7 homolog, CD80, CD28, CTLA4 receptor

Note. Unlike other markers, CD64 and PD-1L do not indicate a state of activation. CD = clusters of differentiation;CTLA 4 = cytotoxic T-lymphocyte antigen 4; Fc = fragment crystallizable; HLA = human leukocyte antigen; IgG = Immunoglobulin G; IL-2 = interleukin 2; MHC = major histocompatibility complex; PD-1L = programmed cell death ligand 1.