Table 1.

Summary of the four Inner City Asthma Consortium cockroach immunotherapy studies. Reproduced with permission from [15]

	SCSS	BioCSI	BioCSI2	SCITCO
Treatment	SLIT	SLIT	SLIT	SCIT
Design	Open label, single site	DBPC, multi- center	DBPC, low and higher dose, multi-center	Open label, single site
CR antigen dose	Bla g 2 – 4.2 µg Bla g 1 – 50 µg	Bla g 2 – 4.2 µg Bla g 1 – 50 µg	Low: Bla g 2 – 4.2 µg Bla g 1 – 50 µg High: Bla g 2 – 16.8 µg Bla g 1 – 202 µg	Bla g 2 – 6 µg Bla g 1 – 120 µg
Primary outcome	Adverse events	Δ in CR-specific IgE	Δ in CR-specific IgE	Adverse events
Treatment Duration	14 days	6 months	3 months	6 months
Participant Ages	Children and adults	Adults	Children	Adults
Sample Size	27	54	99	10