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. 2014 Oct 29;4:6816. doi: 10.1038/srep06816

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(a) Immunofluorescent images showing a marked increase in the expression of ABCG2, a chemoresistant phenotype, in rs-monolayer cells compared to the parental population in multiple cell lines. (b) Difference in the chemosensitivity of parental and rs-monolayer population of Huh7 cells to the antiglycolytic agent 3-BrPA. An increase in IC₅₀ of rs-monolayer cells compared to the parental population indicate the requirement of higher concentration of 3-BrPA to achieve similar toxicity. Scale bar represents 20 µm.