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Antiproliferative effect of A77 1726. A375 cells were seeded in 96-well plates (2000 cells per well) and incubated at the indicated concentrations of A77 1726 for 72 hours in the absence or presence of various concentrations of PLX4720 with (A) or without uridine (200 μM) (B). Cell proliferation was analyzed by an ATP-based Cell-Glo assay. Data from one representative of three experiments with similar results were shown.
