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. Author manuscript; available in PMC: 2014 Oct 29.
Published in final edited form as: Cochrane Database Syst Rev. 2004;(1):CD001884. doi: 10.1002/14651858.CD001884.pub2
Methods Methods of randomisation and allocation concealment were not described
Participants 20 patients undergoing bimaxillary osteotomy were randomly assigned to one of two groups

  1. Desmopressin (DDAVP) group: n = 10; M/F = 1/9.

  2. Control group (No DDAVP) group: n = 10; M/F = 4/6.


NB: Age of patients was not reported.
Interventions

  1. DDAVP group received 20 ug of DDAVP mixed in 50 ml of normal saline, administered IV over one-half hour prior to the surgical procedure.

  2. Control group did not receive DDAVP.


NB: Both groups were exposed to pre-operative autologous blood donation (PAD)
Outcomes Number of patients transfused allogeneic blood (n)
Amount of allogeneic and autologous blood transfused (units)
Blood loss (ml)
Hypotension (n)
Notes Quality assessment score (Schulz criteria): 2/7
Transfusion protocol not specified.
Risk of bias
Item Authors’ judgement Description
Adequate sequence generation? Unclear Method of randomisation was not described.
Allocation concealment? Unclear B - Unclear
Blinding?
All outcomes		 No Studied an untreated control group.