Methods	Method of randomisation and allocation concealment was not described
Participants	44 patients who had taken acetylsalicylic acid within 7 days of scheduled coronary bypass surgery were randomly assigned to one of two groups: Desmopressin (DDAVP) group: n = 20; M = 20; mean age = 56.6 years (range, 52.9-60.3) Placebo group: n = 24; M = 24; mean age = 61.6 years (range, 58.6-64.6)
Interventions	DDAVP group received 10 ug of DDAVP per/metre squared (body surface area) diluted in saline, infused intravenously over 20 minutes after the completion of cardiopulmonary bypass and reversal of heparinisation. Placebo group received equivalent volumes of saline.
Outcomes	Number of patients transfused allogeneic blood (n) Amount of allogeneic blood transfused (units) Number of patients transfused fresh frozen plasma (n) Number of patients transfused platelets (n) Blood loss (mls) Mortality (n) Stroke (n)
Notes	Quality assessment score (Schulz criteria): 4/7 Transfusion protocol not specified.
Risk of bias
Item	Authors’ judgement	Description
Adequate sequence generation?	Unclear	Method of randomisation was not described.
Allocation concealment?	Unclear	B - Unclear
Blinding? All outcomes	Yes	Double blind.