Methods | The pharmacy provided bottles containing placebo or desmopressin (DDAVP) that were identical in appearance. A card drawn at random at the beginning of the operation determined which vial was to be used for the patient. The method used to generate allocation sequences was not described | |
Participants | 83 consecutive patients having open heart surgery were randomly allocated to one of two groups
NB: No patient demographic data were reported. |
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Interventions |
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Outcomes | Number of patients transfused allogeneic blood (n) Number of patients transfused fresh frozen plasma (n) Number of patients transfused platelets (n) Blood loss (ml) Amount of autotransfusion (ml) Number of patients treated with EACA |
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Notes | Quality assessment score (Schulz criteria): 4/7 Transfusion protocol not specified. |
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Risk of bias | ||
Item | Authors’ judgement | Description |
Adequate sequence generation? | Unclear | Method of randomisation was not described. |
Allocation concealment? | Unclear | B - Unclear |
Blinding? All outcomes |
Yes | Double blind. |