. Author manuscript; available in PMC: 2014 Oct 29.

Published in final edited form as: Cochrane Database Syst Rev. 2004;(1):CD001884. doi: 10.1002/14651858.CD001884.pub2

Comparison 2. Adverse events and other outcomes.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Re-operation for bleeding	11	778	Risk Ratio (M-H, Random, 95% CI)	0.69 [0.26, 1.83]
2 Mortality	12	1061	Risk Ratio (M-H, Random, 95% CI)	1.72 [0.68, 4.33]
3 Myocardial infarction	12	876	Risk Ratio (M-H, Random, 95% CI)	1.38 [0.77, 2.50]
4 Stroke (CVA)	5	360	Risk Ratio (M-H, Random, 95% CI)	2.40 [0.68, 8.43]
5 Any thrombosis	9	691	Risk Ratio (M-H, Random, 95% CI)	1.46 [0.64, 3.35]
6 Hypotension - during DDAVP/ Placebo infusion requiring treatment (fluids and/or vasoactive drugs)	5	183	Risk Ratio (M-H, Random, 95% CI)	2.81 [1.50, 5.27]