Methods | Patients were randomly assigned to study drug or placebo by a system of sealed envelopes. The placebo solution was identical in appearance to the study drug solution. The method used to generate allocation sequences was not described | |
Participants | 40 patients undergoing elective primary coronary artery bypass graft surgery were randomly assigned to one of two groups
|
|
Interventions |
NB: Both groups were exposed to cell salvage. |
|
Outcomes | Number of patients transfused allogeneic blood (n) Amount of allogeneic blood transfused (units)xbr Fresh frozen plasma (units) Platelets (units) Blood loss (ml) Re-operation for bleeding (n) Hypotension (n) |
|
Notes | Quality assessment score (Schulz criteria): 5/7 Transfusion protocol not specified. |
|
Risk of bias | ||
Item | Authors’ judgement | Description |
Adequate sequence generation? | Unclear | Method of randomisation was not described. |
Allocation concealment? | No | C - Inadequate. Allocation concealment was by means of sealed envelopes |
Blinding? All outcomes |
Yes | Double blind. |