Table 4.
Genotype and Allele frequencies of rs2681472 in Women With Early-Onset Preeclampsia and Controls in First Stage Study.
| Model | Control (N = 703) | Early-onset PE (N = 260) | P | OR (95% CI) |
|---|---|---|---|---|
| Additive | .032 | NA | ||
| CC | 89 | 28 | ||
| CT | 334 | 104 | ||
| TT | 280 | 128 | ||
| Dominant | .009 | 1.47 (1.10-1.95) | ||
| CC + CT | 423 | 132 | ||
| TT | 280 | 128 | ||
| Recessive | .425 | 1.20 (0.77-1.89) | ||
| CC | 89 | 28 | ||
| CT + TT | 614 | 232 | ||
| Allele | .02 | 1.29 (1.04-1.59) | ||
| C | 512 | 160 | .035a | |
| T | 894 | 360 |
Abbreviations: PE, preeclampsia; OR, odds radio between case and control group; CI, confidence interval; NA, not applicable.
a P value was adjusted for maternal age, prepregnancy body mass index, and primiparity.