Figure 10.

A schematic drawing illustrating the relative positions of 2 consensus estrogen responsive elements (ERE1 and ERE2) in the mouse Greb1 upstream regulatory regions (A). Chromatin immunoprecipitation (ChIP) assays reveal that ESR1 but not ESR2 binding to both EREs in the Greb1 promoter in mouse Sertoli cell line TM4 (B). Genomic DNA input and rabbit immunologublin G (IgG) serve as a positive and a negative control, respectively. ESR indicates estrogen receptor; ERE, estrogen response element.