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. 2014 Jan 13;1(2):88–98. doi: 10.1002/acn3.28

Figure 7.

Figure 7

CERS2 KO mice exhibit increased sensitivity to light. Sensitivity to light was assessed by measuring freezing behavior, an index of fear, in a circular open field under two illumination conditions, dark (10 lux, 5 min) and light (120 lux, 5 min). ANOVA for GENE (KO/HT/WT) indicated no difference in freezing duration in the DARK (F(2,15) = 3.185; n.s.), but a statistically longer duration of freezing in CerS2 null mice than in both WT and heterozygote mice under light. N = 6. (ANOVA for GENE: F(2,15) = 4.42; P < 0.05; Dunnet post-hoc test: KO>het P < 0.05, KO>WT P < 0.05).