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. 2014 Jan 13;1(2):107–114. doi: 10.1002/acn3.30

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© 2014 The Authors. Annals of Clinical and Translational Neurology published by Wiley Periodicals, Inc on behalf of American Neurological Association.

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Significant increase in diagnostic accuracy combining magnetic resonance spectroscopy (MRS) and diffusion tensor imaging (DTI) measures. Receiver operating characteristic (ROC) curves comparing DTI diagnostic test accuracy model to combined DTI and MRS model. Solid ROC curve represents the model using DTI fractional anisotropy values. Dashed ROC curve represents the model using DTI fractional anisotropy, MRS N-acetylaspartate, MRS myo-inositol, and MRS γ-aminobutyric acid values combined.