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. 2014 Jan 9;1(2):130–134. doi: 10.1002/acn3.31

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© 2014 The Authors. Annals of Clinical and Translational Neurology published by Wiley Periodicals, Inc on behalf of American Neurological Association.

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Case no. 9. (A) Representative BRAFV600E mutated LEAT: the tumor is a grade II pleomorphic xanthoastrocytoma composed of giant neoplastic cells showing nuclear pleomorphism and xanthomatous changes; nuclear inclusions and numerous eosinophilic granular bodies are present; in spite of marked cytological pleomorphism the tumor lacks microvascular proliferation and necrosis; mitotic figures are not common (H&E, 200× magnification); (B) corresponding BRAFV600E mutated associated FCD: dysmorphic neurons in focal cortical displasia type IIa (H&E, 200× magnification).