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. 2014 Sep 18;6(5):54. doi: 10.1186/s13195-014-0054-5

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Copyright © 2014 Song et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Risk-factor indices in relation to age. The indices containing vascular risk factors (VRFIs; n = 4), nontraditional risk factors (NTRFIs; n = 19), and all risk factors (ARFIs; n = 42) are presented as a function of age in men (green) and in women (red). Symbols represent the observational data as means for 3-year age groups; lines represent curve fitting. The nontraditional and all factor indices increased exponentially with age (for example, R² = 0.981 in men and R² = 0.939 in women for the NTRFI; R² = 0.982 in men and R² = 0.987 in women for the ARFI; P < 0.001 in each case).