Table 1.
No. Trivial name | Structure | Ceramidea) | Effectb) | Source |
---|---|---|---|---|
1. Native sulfatide | SO3-3Galβ1Cer | d18:1-mixture | + + | Porcine brain |
2. Lysosulfatide | SO3-3Galβ1Sph | d18:1 | + + + + | Semi-synthetic |
3. Sulfatide C8:0 | SO3-3Galβ1Cer | d18:1–8:0 | + | Semi-synthetic |
4. Sulfatide C12:0 | SO3-3Galβ1Cer | dl8:1–12:0 | + + | Semi-synthetic |
5. Sulfatide C16:0 | SO3-3Galβ1Cer | d18:1–16:0 | + | Semi-synthetic |
6. Sulfatide C18:1 | SO3-3Galβ1Cer | d18:1–18:1 | + | Semi-synthetic |
7. Sulfatide C24:0 | SO3-3Galβ1Cer | d18:1–24:0 | + + | Semi-synthetic |
8. Sulfatide C24:1 | SO3-3Galβ1Cer | d18:1–24:1 | + + + | Semi-synthetic |
9. Sulfatide | SO3-3Galβ1Cer | d18:1-h24:0 | − | Human intestine |
10. Sulfatide | SO3-3Galβ1Cer | t18:0-h16:0 | − | Human intestine |
11. Sulfatide | SO3-3Galβ1Cer | t18:0-h24:0 | − | Human intestine |
In the shorthand nomenclature for fatty acids and bases, the number before the colon refers to the carbon chain length and the number after the colon gives the total number of double bonds in the molecule. For long chain bases, d denotes dihydroxy and t denotes trihydroxy. Thus, d18:1 designates sphingosine (1,3-dihydroxy-2-aminooctadecene) and t18:0 phytosphingosine (1,3,4-trihydroxy-2-aminooctadecane). Fatty acids with a 2-hydroxy group are denoted by the prefix h before the abbreviation e.g. h16:0.
Summary of the relative stimulatory effect in the assays with different APC and XV19 hybridoma responder cells.