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. Author manuscript; available in PMC: 2014 Oct 29.
Published in final edited form as: Eur J Immunol. 2009 Jul;39(7):1726–1735. doi: 10.1002/eji.200839001

Table 1.

Sulfatide isoforms tested for stimulation of XV19 hybridoma cells.

No. Trivial name Structure Ceramidea) Effectb) Source
1. Native sulfatide SO3-3Galβ1Cer d18:1-mixture + + Porcine brain
2. Lysosulfatide SO3-3Galβ1Sph d18:1 + + + + Semi-synthetic
3. Sulfatide C8:0 SO3-3Galβ1Cer d18:1–8:0 + Semi-synthetic
4. Sulfatide C12:0 SO3-3Galβ1Cer dl8:1–12:0 + + Semi-synthetic
5. Sulfatide C16:0 SO3-3Galβ1Cer d18:1–16:0 + Semi-synthetic
6. Sulfatide C18:1 SO3-3Galβ1Cer d18:1–18:1 + Semi-synthetic
7. Sulfatide C24:0 SO3-3Galβ1Cer d18:1–24:0 + + Semi-synthetic
8. Sulfatide C24:1 SO3-3Galβ1Cer d18:1–24:1 + + + Semi-synthetic
9. Sulfatide SO3-3Galβ1Cer d18:1-h24:0 Human intestine
10. Sulfatide SO3-3Galβ1Cer t18:0-h16:0 Human intestine
11. Sulfatide SO3-3Galβ1Cer t18:0-h24:0 Human intestine
a)

In the shorthand nomenclature for fatty acids and bases, the number before the colon refers to the carbon chain length and the number after the colon gives the total number of double bonds in the molecule. For long chain bases, d denotes dihydroxy and t denotes trihydroxy. Thus, d18:1 designates sphingosine (1,3-dihydroxy-2-aminooctadecene) and t18:0 phytosphingosine (1,3,4-trihydroxy-2-aminooctadecane). Fatty acids with a 2-hydroxy group are denoted by the prefix h before the abbreviation e.g. h16:0.

b)

Summary of the relative stimulatory effect in the assays with different APC and XV19 hybridoma responder cells.