Table 5.

Effects of the aqueous extract of F. glumosa on index kidney function.

Drugs (mg/kg)	Control	225 mg/kg	300 mg/kg	375 mg/kg	Furosemide (2 mg/kg)	Amiloride H. (14 mg/kg)
Creatinine (mg/24 h)	24.66 ± 4.93	17.66 ± 1.52∗∗∗	21 ± 2.64∗∗	25.00 ± 3.60∗	20.00 ± 4.35∗∗	26.33 ± 5.50
CreatC (mL/min)	0.027 ± 0.02	0.024 ± 0.06∗	0.021 ± 0.04∗∗	0.019 ± 0.03∗∗∗	0.020 ± 0.02∗∗	0.019 ± 0.04∗∗∗
Urea (g/24 h)	26.33 ± 3.21	22.33 ± 1.52∗∗∗	23.00 ± 4.35∗	25.66 ± 4.72	23.66 ± 1.52∗∗	21.33 ± 1.52∗∗∗
Uosm (mosmol/kg)	199 ± 17	109 ± 18∗∗∗	111 ± 13∗∗∗	121 ± 17∗∗∗	169 ± 28∗∗∗	157 ± 12∗∗∗
GFR (mL/min)	1.60 ± 0.51	1.53 ± 0.32∗	1.50 ± 0.12∗	1.40 ± 0.14∗∗	1.35 ± 0.17∗∗∗	1.30 ± 0.22∗∗∗
Cosm (mL/min)	0.046 ± 0.005	0.044 ± 0.011	0.045 ± 0.015	0.047 ± 0.007∗∗	0.075 ± 0.011∗∗∗	0.065 ± 0.009∗∗∗
CH2O. (mL/min)	0.055 ± 0.011	0.053 ± 0.014	0.055 ± 0.021	0.065 ± 0.006∗∗∗	0.067 ± 0.012∗∗∗	0.065 ± 0.014∗∗∗

Values are means ± SEM, n = 5, ∗ < 0.05, ∗∗ < 0.01, ∗∗∗ < 0.001, significant difference compared to the control.

CreatC: creatinine clearance; Uosm: urinary osmolarity;

GFR: glomerular filtration rate; Cosm: osmolar clearance;

C_H2O: free water clearance.