Table 3.
Physiological parameters and organ support at initiation of PSV
| Neurological | |
|---|---|
| RASS | −2 (−2 to −3) |
| RASS −5 | 2 (1) |
| RASS −4 | 18 (9) |
| RASS −3 | 70 (34) |
| Sedation in 24 h prior to PSV | |
| Propofol (mg) | 730 (240–1690) |
| Fentanyl (µg) | 400 (0–1175) |
| Respiratory | |
| PaO2:FiO2 (kPa) | 35.8±15.9 |
| PEEP (cm H2O) | 7.5±2.5 |
| pH | 7.35±0.07 |
| PaCO2 (kPa) | 5.7±1.3 |
| Cardiovascular | |
| HR (bpm) | 88±17 |
| MAP (mm Hg) | 77±11 |
| Requiring vasoactive drugs | 88 (42) |
| SOFA* | |
| SOFA (total) | 6 (4–8) |
| Respiratory | 1 (1–3) |
| Cardiovascular | 1 (1–3) |
| Renal | 0 (0–2) |
| Hepatic | 1 (0–1) |
| Haematological | 0 (0–2) |
| GCS† | 0 (0–0) |
Data are presented as mean±SD or median (IQR). n=209.
*n=199.
†Assumed GCS not accounting for sedation.
FiO2, fraction of inspired oxygen; GCS, Glasgow Coma Scale; HR, heart rate; MAP, mean arterial pressure; PaCO2, partial pressure arterial carbon dioxide; PaO2, partial pressure arterial oxygen; PEEP, positive end-expiratory pressure; PSV, pressure support ventilation; RASS, Richmond Agitation and Sedation Scale; SOFA, sequential organ failure assessment.