Table 5.
Logistic regression analysis of independent risk factors for PSV failure
| Parameter | Univariate analysis |
Multivariate analysis |
||
|---|---|---|---|---|
| OR (95% CI) | p Value | OR (95% CI) | p Value | |
| Age (years) | 1.002 (0.983 to 1.022) | 0.83 | 0.77 | |
| APACHE II | 1.035 (0.984 to 1.089) | 0.18 | 0.61 | |
| Chronic respiratory disease | 1.037 (0.519 to 2.075) | 0.92 | 0.76 | |
| Chronic cardiovascular disease | 0.731 (0.374 to 1.428) | 0.36 | 0.8 | |
| Time to initiation of PSV (h) | 0.996 (0.982 to 1.011) | 0.63 | 0.57 | |
| RASS ≤3 | 1.533 (0.819 to 2.868) | 0.18 | 0.54 | |
| PEEP >5 cm H2O | 1.513 (0.783 to 2.923) | 0.22 | 0.52 | |
| PaO2:FiO2 ≤26 kPa | 1.841 (0.955 to 3.546) | 0.07 | 0.1 | |
| pH | 0.996 (0.993 to 0.998) | 0.002 | 0.996 (0.993 to 0.998) | 0.002 |
| PCO2 (kPa) | 1.146 (0.911 to 1.441) | 0.24 | ||
| Respiratory acidosis | 2.060 (0.835 to 5.083) | 0.12 | ||
| Cardiovascular instability | 1.829 (0.969 to 3.451) | 0.06 | 0.06 | |
n=196. Missing data point for one of the predicting variables n=13.
APACHE II, Acute Physiology and Chronic Health Evaluation; FiO2, fraction of inspired oxygen; PaCO2, partial pressure arterial carbon dioxide; PaO2, partial pressure arterial oxygen; PEEP, positive end-expiratory pressure; PSV, pressure support ventilation; RASS, Richmond Agitation and Sedation Scale.