. 2014 Oct 8;62(43):10452–10457. doi: 10.1021/jf5026086

Table 2. In Vitro COX-2 Enzyme Inhibition by the Ethanolic Extract of Grains of Paradise and Its Anti-inflammatory Components^a.

treatment	inhibition (%) ± SD
control^b	2 ± 2
A. melegueta extract	76 ± 6.7***
[6]-gingerol	7 ± 11.7
[6]-shogaol	68 ± 6.4***
[6]-paradol	91 ± 3.6***
Vioxx	87 ± 1.5***

Data are shown as mean inhibition ± SD in %. Significance: ***, 0.1%.

All samples were tested at the concentration of 1 mg/mL. Control, celery extract at 1 mg/mL; whole extract, grains of paradise (A. melegueta) extract at 1 mg/mL; Vioxx (MW 314.36) at 1 mg/mL, 3.18 mM; [6]-gingerol (MW 294.38) at 1 mg/mL, 3.39 mM; [6]-shogaol (MW 276.37) at 1 mg/mL, 3. 62 mM; [6]-paradol (MW 278) at 1 mg/mL, 3.60 mM.

Table 2. In Vitro COX-2 Enzyme Inhibition by the Ethanolic Extract of Grains of Paradise and Its Anti-inflammatory Componentsa.

Table 2. In Vitro COX-2 Enzyme Inhibition by the Ethanolic Extract of Grains of Paradise and Its Anti-inflammatory Components^a.