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. 2014 Oct 9;8(10):10998–11006. doi: 10.1021/nn505162u

Figure 1.

Figure 1

Laboratory-built HSFCM system and preliminary performance evaluation. (a) Schematic diagram of the laboratory-built apparatus and the structure of a nanomedicine. (b) Representative side-scatter and fluorescence (524/24 band pass) burst traces of 80 nm diameter fluorescent silica nanoparticles (425 MESF AF532) at a laser power of 16 mW, with a focused laser spot of 16 μm. (c) Effect of the laser power on the signal-to-noise ratios of the SS and FL detection of the 80 nm fluorescent silica nanoparticles. The focused laser spot was 6.4 μm, and a neutral density filter (OD = 1.3) was placed in the SS light path to avoid APD saturation.