Table 1.
Descriptive statistics and association analysis for inflammation biomarker and potential intervening variables stratified by the four study groups
| Controls (n = 84) |
Depressed- only (n =8) |
Maltreated- only (n = 69) |
Depressed + maltreated (n = 13) |
P-value | |
|---|---|---|---|---|---|
| Panel 1: Inflammation biomarker | |||||
| CRP, geometric mean (95% CI) | 0.28 | 0.25 | 0.28 | 0.49 | 0.016 |
| (0.24–0.33)a | (0.16–0.38)a | (0.23–0.35)a | (0.28–0.84)a | ||
| P-valueb | — | 0.587 | 0.937 | 0.045 | |
| Panel 2: Matching variables | |||||
| SES, mean (s.d.) | 1.76 (0.82) | 1.50 (0.93) | 1.61 (0.83) | 1.77 (0.60) | 0.592 |
| Male sex, n (%) | 39 (46.4) | 5 (62.5) | 38 (55.1) | 4 (30.8) | 0.316 |
| Dizygotic twin, n (%) | 47 (56.0) | 7 (87.5) | 40 (58.0) | 8 (61.5) | 0.383 |
| Panel 3: Potential intervening variables | |||||
| Body temperature, mean (s.d.) | 36.37 (0.40) | 36.04 (0.51) | 36.36 (0.46) | 36.47 (0.26) | 0.147 |
| Waist–hip ratio, mean (s.d.) | 0.84 (0.07) | 0.84 (0.09) | 0.85 (0.06) | 0.83 (0.06) | 0.616 |
Abbreviations: CI, confidence interval; CRP, C-reactive protein; SES, socioeconomic status.
a
Confidence intervals are adjusted for the effect of familial clustering.
b
P-values from a-priori defined contrasts testing differences between single study groups and control group, adjusted for the effect of familial clustering.