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Number and percentage positive staining for p16, EGFR, p53, and Cyclin D1 based on benign versus inverted papilloma with carcinogenesis. NS=no statistical significance.
| Benign IP | IP with carcinoma |
Significance | |
|---|---|---|---|
| p16 + (%) | 85/133 (64%) | 3/21 (14%) | p<0.001 |
| EGFR+ (%) | 68/135 (50%) | 15/21 (71%) | NS |
| P53+ (%) | 45/135 (30%) | 13/21 (62%) | p<0.001 |
| Cyclin D1+ (%) | 104/136 (76%) | 16/21 (76%) | NS |
