Table 1.

Dietary and supplemental vitamin intake as median [range] by Dietary Reference Intake criteria

	Baseline			12 Months
	All n=58	LYX n=23	Placebo Comparison Group n=35	All	LYX	Placebo Comparison Group
Vitamin A, % RDA
Diet	165 [46 – 500]	163 [70 – 296]	176 [46 – 500]	128 [44 – 438]*	126 [61 – 337]	131 [44 – 438]*
Supplement	555 [0 – 1284]	548 [0 – 1284]	616 [130 – 1232]	456 [0 – 1235]	492 [130 – 840]	420 [0 – 1235]
Total	723 [105 – 1722]	718 [105 – 1442]	765 [315 – 1722]	673 [120 – 1462]*	676 [211 – 1168]	654 [120 – 1462]*
Vitamin D, % RDA
Diet	44 [12 – 171]	46 [22 – 171]	41 [12 – 111]	37 [9 – 136]	38 [9 – 112]	36 [11 – 136]
Supplement	133 [44 – 1500]	133 [67 – 1433]	133 [44 – 1500]	167 [0 – 1500]	167 [67 – 333]	167 [0 – 1500]
Total	195 [71 – 1611]	194 [92 – 1477]	196 [71 – 1611]	207 [30 – 1624]	207 [87 – 409]	207 [30 – 1624]
Vitamin E, % RDA
Diet	88 [27 – 893]	86 [50 – 247]	89 [27 – 893]	71 [31 – 574]	71 [48 – 255]	71 [31 – 574]
Supplement	1619 [0 – 3810]	1273 [0 – 3810]	1818 [182 – 3810]	1273 [0 – 3111]	1212 [182 – 2424]	1905 [0 – 3111]
LXS/Placebo	0	0	0	72 [3 – 160]	100 [3 – 160]§	56 [12 – 89]§
Total	1851 [62 – 4703]	1345 [62 – 3910]	1896 [350 – 4703]	1494 [71 – 3178]	1302 [331 – 2660]	2025 [71 – 3178]
Vitamin K, % AI
Diet	95 [27 – 397]	95 [55 – 252]	87 [27 – 397]	96 [30 – 1233]	117 [47 – 1233]	85 [30 – 285]
Supplement	500 [0 – 9404]	500 [0 – 3000]	667 [0 – 9404]	1333 [0 – 9455]	1067 [0 – 2667]§	2333 [0 – 9454]§
Total	689 [63 – 9535]	578 [63 – 3094]	1064 [85 – 9535]	1430 [43 – 9593]	1292 [125 – 2797]§	2395 [43 – 9593]§

RDA: Recommended Daily Allowance; AI: Adequate Intake

^*p<0.05, the difference between baseline and 12 months within each group (all, LXS, or placebo);

^§p<0.05 for the difference between LXS and comparison group at 12 month

Note: LXS and comparison intakes are adjusted for adherence