Table 3. Clinical Risk Factors and Health Outcomes for Bronchiolitis.
| Bronchiolitis Score (severity) | 0–1 (none or trivial) | 2 (mild) | 3 (moderate) | 4+ (severe) | P value for trend |
| No of Patients | 1,013 (70%) | 362 (25%) | 58 (4%) | 13 (1%) | – |
| Women | 297 (29%) | 104 (29%) | 12 (21%) | 4 (31%) | 0.3817 |
| Age (years) | 48.4±8.0 | 48.5±7.0 | 47.0±5.8 | 48.4±6.6 | 0.5201 |
| Current Smokers | 271 (27%) | 225 (64%) | 50 (89) | 12 (92%) | <.0001 |
| Intravenous Drug Use | 235 (23%) | 130 (36%) | 30 (52%) | 8 (62%) | <.0001 |
| HIV exposure (months) | 197±76 | 210±71 | 236±71 | 230±63 | <.0001 |
| Nadir CD4 Count (cells/mm3) | 198±152 | 200±182 | 164±167 | 179±111 | 0.3589 |
| Current CD4 Count (cells/mm3) | 598±265 | 654±310 | 622±298 | 548±243 | 0.0438 |
| Body mass index (kg/m2) | 24.1±3.9 | 23.1±3.3 | 22.1±3.2 | 22.0±3.5 | <.0001 |
| Subcutaneous Adipose Tissue (cm2) | 161±97 | 135±82 | 118±83 | 98±72 | <.0001 |
| Visceral Adipose Tissue (cm2) | 136±80 | 122±65 | 113±67 | 106±52 | 0.0003 |
| Prior PJP infection | 74 (8%) | 20 (6%) | 8 (15%) | 2 (15%) | 0.0823 |
| Prior Pneumonia | 95 (11%) | 57 (18%) | 7 (13%) | 0 (0%) | 0.0074 |
| CRP (>1.1 mg/L) | 442 (47%) | 178 (53%) | 30 (56%) | 9 (75%) | 0.0443 |
| WBC (/µL) | 5992±1768 | 6723±2293 | 7660±2269 | 7509±2433 | <.0001 |
| FEV1 (% predicted) | 104.7±16.3 | 106.2±18.3 | 104.7±20.1 | 96.2±16.1 | 0.8522 |
| FEV1/FVC (%) | 79.1±6.9 | 79.4±6.3 | 78.6±7.4 | 75.8±7.4 | 0.8539 |
| DLCO (% predicted) | 76.0±16.5 | 73.3±16.0 | 67.9±11.4 | 71.2±13.3 | 0.0475 |
| Emphysema Score | 0.52±0.97 | 1.05±1.20 | 1.55±1.17 | 1.85±0.97 | <.0001 |
| Regular physical activity * | 465 (47%) | 149 (43%) | 11 (20%) | 1 (8%) | <.0001 |
Dichotomous data are presented as number of individuals (% column totals) and continuous variables are presented as mean±SD for normally distributed variables or median (interquartile range) for non-normally distributed variables.
*2 or more hours of physical activity per week.
Abbreviations: CRP, C-reactive protein; DLCO, diffusing capacity of lung for carbon monoxide or transfer factor; FEV1, forced expiratory volume in one second; FVC, forced vital capacity; HIV, human immune deficiency; PJP, pneumocystis jiroveci pneumonia.