Table 1.

Baseline Clinical Characteristics and Treatment Response

Characteristics	All
Gender, No. (%)
Male	15 (53.5)
Female	13 (46.5)
Mean Age, (range)	59±9 (41-78)
Age, y, no (%)
<60 y	13 (46.5)
≥60 y	15 (53.5)
ECOGa Performance status, No. (%)
0	3 (10.7)
1	25 (89.3)
Smoking, No. (%)
Never smoker	17 (60.7)
Smoker	11 (39.3)
Histology, No. (%)
Adenocarcinoma	20 (71.4)
Squamous cell carcinoma	6 (21.4)
Poorly differentiated carcinoma	2 (7.1)
Clinical Response, No. (%)
PRb	19 (67.8)
SDc	9 (32.2)
Post operative T, No. (%)
T1	19 (67.8)
T2	8 (28.6)
T3	1 (3.6)
T4	0 (0.0)
Post operative N, No. (%)
N0	19 (67.8)
N1 or N2	9 (32.2)
Infiltrating macrophages, medium, (IQRd)
Stromal macrophage	121 (59-164)
Islet macrophage	105 (63-144)
Islet/Stromal macrophage	1.21 (0.43-1.83)
Total macrophage	228 (154-321)
Disease Free Survival, Median, (95% CI)	13.1 (5.0-21.3)
Overall Survival, Median, (95% CI)	36.8 (28.2-45.7)

^aECOG: Eastern Cooperative Oncology Group;

^bPR: partial response;

^cSD: stable disease;

^dIQR: interquartile range.