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. 2014 Oct 2;143(3):478–489. doi: 10.1111/imm.12328

Figure 3.

Figure 3

miR-155−/− mice show diminished expression of interleukin-17A+ (IL-17A+) expressing CD4+ T cells. Spleen, mesenteric lymph nodes (MLN) and lamina propria (LP) lymphocytes were isolated from all groups of mice at the experimental end point, as described in Fig.1. Changes in the frequency and expression of IL-17A+ expressing CD4+ T cells from spleen lymphocyte, MLN and LP are shown in (a). The numbers in the upper right quadrant indicate the total percentage of IL-17A+ cells (a). Changes in the number of CD4+ T cells expressing IL-17A are shown in (b). Experiments involved six mice per group. Asterisks indicate statistically significant differences between wild-type and miR-155−/− groups; i.e. *P < 0·01.