Table 2.

Instruments available for each data source

Source	Pain	Disability	Joint swelling/tenderness	Patient global
Merck, Sharp & Dohme	Likert 0–4	No measure available	Likert 0–3*	Response to treatment (Likert 0–4 point)
Pfizer	Likert 0–4	No measure available	Likert 0–3*	Response to treatment (Likert 0–4 point)
Regeneron	Likert 0–4 NRS 0–10	Activity limitations NRS 0–10 (from WPAI:SHP v2.0)	No measure† available	No measure† available
Novartis	Likert 0–4 VAS 0–100	HAQ-DI	Likert 0–3*	Response to treatment (Likert 0–4 point)
Auckland University of Technology	VAS 0–100	HAQ-II	Swollen and tender joint count	VAS 0–100

HAQ-II Health Assessment Questionnaire version II; HAQ-DI, Health Assessment Questionnaire Disability Index; VAS Visual Analog Scale; WPAI:SHP Worker Productivity and Activity Impairment Index (Specific Health Problem) (8).

^*Index joint assessed by a physician;

^†a Likert 0–3 grade for joint tenderness and swelling was used in the actual trial but those data were not available for the current analysis