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. 2014 Oct 29;9(10):e111135. doi: 10.1371/journal.pone.0111135

Figure 3. QPCR quantification of guinea pig Abcb1 isoforms in guinea pig placenta and brain.

Figure 3

A. Schematic diagram of QPCR primer pairs used to determine the relative abundance of Abcb1 isoforms 1 and 2 and isoforms 1 and 3. Diagonal lines between exons 30 and 31 represent a longer region than can be represented here. B. Bar graph of relative abundance of isoforms 1 and 2 in individual placenta and brain MV samples following QPCR with primer pairs shown in A. Differences in brain magnified in inset. C. Bar graph of average relative abundance of isoforms 1 and 3 in placental samples (Ci) and brain MV samples (Cii) following QPCR with primer pairs shown in A. All bars represent mean ± SEM. *P<0.05 as determined by Student’s t-test.