Table 2. Summary of guinea pig Abcb1 isoform characteristics. *Isoforms 1 and 3 use the same stop codon.
Isoform | Size ofmRNA (nt) | Exons 3 to 28identical | Size ofexon 29(nt) | Exon 30 | Exon 31 | Stopcodonposition | PolyAsequences | Predominantlyexpressed in | Protein (aa) |
Isoform 1 | 6527 | Yes | 2781 | Yes | No | 3,817* | Yes | Placenta | 1272 |
Isoform 2 | 3819 | Yes | 118 | No | Yes | 3,817 | No | 1272 | |
Isoform 3 | 4168 | Yes | 553 | No | No | 3,817* | No | Brain | 1272 |