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. 2014 Oct 29;9(10):e111177. doi: 10.1371/journal.pone.0111177

Figure 2. miR-101 induces senescence and not apoptosis in MCF7 cells.

Figure 2

(a) Original Flow-cytometry dot-blot of PI Staining Vs Annexin-V Staining, (b) Percentage of Annexin-V positive (apoptotic) and negative cells, (c) β-gal positively stained (senescent) cells, (d) Fold change in number of senescent cells, under control (mock-pEP-Null-transfected, mock-DMSO treated & mock negative with scrambled primers) and experimental conditions (pEP-miR-101 transfection, Etoposide 1 µM treatment & anti-miR-101 transfection). Time dependent increase in senescence in miR-101 transfected cells is also shown (d).