Figure 1.

Complete consensus sequence of 71 human SDR sequences. Consensus sequences for the human SDR family, constructed using consensus sequence constructor. The highly conserved positions (>70% identity) are marked with bolded black letters as M, G, G, V, and L. Intermediate conservation (>30% identity) is indicated with black characters corresponding to the most commonly occurring residue. The positions marked as X are the variable positions that are occupied by any particular residue in more than 30% of sequences. As a whole, this figure displays the highly variable characteristics of the human SDR family.