Skip to main content
. 2014 Oct 12;6:73–80. doi: 10.4137/PMC.S13215

Table 3.

Selective antimicrobial peptides in clinical trial according to Refs. 5, 92, and 93.

NAME NUMBER OF AMINO ACIDS DESCRIPTION INTENDED USE COMPANY TRIAL PHASE
Omiganan (MBI-226, MX-226, CSL-001) 12 Synthetic analog of indolicidin Topical antiseptic prevention of catheter infection, severe acne and rosacea Migenix/BioWest therapeutics Cutanea Life Sciences III/II
Pexiganan (MSI-78) 22 Synthetic analog of magainin 2 Topical antibiotic – diabetic ulcers Macrochem III
Iseganan (IB-367) 17 Protegrin 1 derivative Prevention of oral mucositis Ardea Biosciences III
LTX-109 3 Peptidomimetic Topical antibiotic Lytic Biopharma I/II
hLF1–11 11 Lactoferrin derivative Prevention of bacteraemia and fungal infections AM Pharma I/II
OP-145 24 LL-37 derivative Treatment of chronic middle ear infection Octoplus I/II