Table 6.
Clusters showing significant differences in participants with bipolar I disorder (BP-I) versus healthy comparison (HC) participants and participants with major depressive disorder (MDD) versus HC participants during circle images (attentional)
| Region of interest | Laterality | Center of mass Talairach coordinates |
Volume (3-mm3 voxels) | Greater activation in | ||
|---|---|---|---|---|---|---|
| x | y | z | ||||
| BP-I versus HC attentional | ||||||
| Superior frontal gyrus | L | +28.5 | +1.5 | +65.5 | 61 | HC |
| Culmen | R | −13.5 | +25.5 | −24.5 | 52 | HC |
| Cingulate gyrus | L | +1.5 | +31.5 | +29.5 | 47 | HC |
| MDD versus HC attentional | ||||||
| Insula | L | +37.5 | −13.5 | −3.5 | 88 | MDD |
| Postcentral gyrus | L | +31.5 | +34.5 | +65.5 | 82 | MDD |
| Middle frontal gyrus | R | −28.5 | −58.5 | +8.5 | 45 | HC |
| Inferior temporal gyrus | R | −55.5 | +1.5 | −33.5 | 37 | HC |
Significant at p = 0.05 at threshold p = 0.005 at cluster threshold of 37. L = left; R = right.