Table 2. Categorization of 65 match runs of heart-liver transplant recipients.
| Variable* | Heart “sequestered” liver, N=42 | Liver “sequestered” heart, N=13** | Equal priority, N=10 | P-value |
|---|---|---|---|---|
| Heart match run position | 2 (1, 4) | 35 (11, 52) | 3 (1, 5) | <0.001 |
| Liver match run position | 138 (49, 450) | 1 (1, 3) | 3 (2, 6) | <0.001 |
| Difference in heart vs. liver match run rank** | -134 (-45, -444) | 33 (8, 49) | 0 (-1, 1) | <0.001 |
| Liver recipient with MELD exceptions, N (%) | 4 (9.5) | 12 (92.3) | 6 (60.0) | <0.001 |
| Laboratory MELD score at transplantation | 15 (11,20) | 10 (8,17) | 13 (9,16) | 0.27 |
| Match MELD score at transplantation | 15 (11,20) | 29 (25,33) | 26 (22,29) | <0.001 |
| Heart status at transplant | <0.001 | |||
| 1a, N (%) | 22 (52.4) | 2 (15.4) | 6 (60.0) | |
| 1b, N (%) | 18 (42.9) | 3 (23.1) | 3 (30.0) | |
| 2, N (%) | 2 (4.8) | 8 (61.5) | 1 (10.0) | |
| Liver diagnosis, N (%) | <0.001 | |||
| Cardiac cirrhosis | 28 (66.7) | 1 (7.7) | 2 (20.0) | |
| Amyloidosis | 5 (11.9) | 10 (76.9) | 6 (60.0) | |
| Hepatitis C | 0 (0.0) | 1 (7.7) | 1 (10.0) | |
| Cryptogenic cirrhosis/NASH | 5 (11.9) | 0 (0.0) | 0 (0.0) | |
| Other | 4 (9.5) | 1 (7.7) | 1 (10.0) | |
| Heart diagnosis, N (%) | 0.001 | |||
| Amyloidosis | 5 (11.9) | 9 (69.2) | 6 (60.0) | |
| Congenital heart disease | 11 (26.2) | 0 (0.0) | 1 (10.0) | |
| Idiopathic dilated cardiomyopathy | 10 (23.8) | 0 (0.0) | 1 (10.0) | |
| Hypertrophic cardiomyopathy | 7 (16.7) | 0 (0.0) | 1 (10.0) | |
| Other | 9 (21.4) | 4 (30.8) | 1 (10.0) | |
| Age at transplant | 47 (35-55) | 50 (46-60) | 60 (42-64) | 0.09 |
*
Median (IQR) unless otherwise specified
**
Difference in heart vs. liver match run rank was the difference between an individual transplant recipient's rank on the heart match run subtracted by their rank on the liver match run
***
In 5 cases, the H-L recipient bypassed the heart match completely