Table 4.
Matched candidate approach #1: Stratified Cox model of waitlist removal for liver waitlist candidates bypassed by H-L recipients when the heart sequestered the liver versus controls selected by match MELD score*
| Variable | Hazard ratio | P-value |
|---|---|---|
| Bypassed waitlist candidate | 0.56 (0.40-0.79) | 0.001 |
| Age at waitlisting | 1.02 (1.01-1.03) | 0.001 |
| Exception MELD score† | 0.11 (0.07-0.16) | <0.001 |
| Race/ethnicity | 0.87 | |
| White | 1 | |
| Black | 0.93 (0.71-1.23) | |
| Hispanic | 0.92 (0.68-1.23) | |
| Asian | 0.79 (0.44-1.40) | |
| Other | 0.82 (0.25-2.70) | |
| Diagnosis | 0.41 | |
| Hepatitis C | 1 | |
| Alcohol | 0.81 (0.63-1.03) | |
| Hepatitis B | 1.09 (0.63-1.87) | |
| NASH/cryptogenic | 0.98 (0.76-1.27) | |
| Cholestatic | 1.00 (0.75-1.33) | |
| Autoimmune | 1.16 (0.71-1.91) | |
| Other | 1.01 (0.72-1.42) | |
| Fulminant hepatic failure | 1.52 (0.94-2.48) |
Controls were liver waitlist candidates matched 8:1 based on blood type, match MELD score, and UNOS region of bypass liver waitlist candidate. Interaction of exception points and bypass candidate versus control was not significant (p=0.8).
Binary yes/no (1/0) as to whether match MELD score was based on exception points.