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Graphic presentation of the binding sites of Eg5 motor based on the crystal structure of monastrol-Eg5 complex (PDB ID: 1Q0B). Eg5 motor was shown in ribbon and colored by secondary structures (α-helix: red; β-sheets: cyan; loops: grey). Monastrol and ADP molecules were represented as solid sticks. The two putative allosteric binding sites, S1 and S2, were illustrated as meshed surfaces.
