. Author manuscript; available in PMC: 2015 Jul 31.

Published in final edited form as: Biometrics. 2014 Apr 29;70(3):489–499. doi: 10.1111/biom.12179

Table 5.

Estimated regression coefficients for the immune response (change in CD4 counts from baseline to week 24) based on the ACTG 320 Data.

Model	Treatment		Intercept	Age	CD4₀	log(CD4₀)	log₁₀(RNA₀)
	2-drug	Estimate	1.065	0.002	0.004	−0.338	0.011
		Std. Error	0.350	0.004	0.001	0.057	0.049
		p-value	0.002	0.568	< 0.001	< 0.001	0.829
M_update
	3-drug	Estimate	1.317	0.009	−0.001	−0.328	0.128
		Std. Error	0.348	0.004	0.001	0.062	0.051
		p-value	< 0.001	0.023	0.199	< 0.001	0.013

	2-drug	Estimate	1.124	0.002	0.004	−0.338
		Std. Error	0.218	0.004	0.001	0.057
		p-value	< 0.001	0.584	< 0.001	< 0.001
M_old
	3-drug	Estimate	1.984	0.008	−0.002	−0.318
		Std. Error	0.225	0.004	0.001	0.062
		p-value	< 0.001	0.035	0.066	< 0.001