Figure 1.

Lesion overlap map and predefined ROIs for generating synthetic scores in simulations. a: Lesion overlap map of 106 subjects. Colorbar on the right indicates the number of lesion subjects. The text above each slice indicates the spatial location of the sagittal slice in the MNI space. b: Three predefined ROIs used for generating the synthetic score in simulations. c: The correlation map between the lesion status of each voxel and the total lesion volume. Correlation coefficients to the total lesion volume for ROI 1∼3 are 0.7301, 0.7002, and 0.2942, respectively. [Color figure can be viewed in the online issue, which is available at http://wileyonlinelibrary.com.]