Skip to main content
. 2014 Sep 5;28(11):1866–1874. doi: 10.1210/me.2014-1204

Figure 3.

Figure 3.

Peripheral 5-HT deficiency down-regulates several key Hh pathway members in the lactating mammary gland. WT mouse dams were given saline and Tph1−/− dams were given either saline or daily injections of exogenous 5-HTP [100 mg/kg; Tph1−/−(5-HTP)] from pregnancy day 13 to lactation day 10. A–C, Shh ligand (exons 1, 2, and 3). D–G, Ptch1, Gli1, Gli2, and Smo mammary gland mRNA expression on day 10 of lactation. All values are reported as means ± SEM (n = 7 per group). *, P < .05; **, P < 0.01.