Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Sep 24;28(11):1820–1830. doi: 10.1210/me.2014-1157

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2014 by the Endocrine Society

PMC Copyright notice

Figure 3. — Effect of proinflammatory cytokines and thapsigargin on ribosomal occupancy of Atf4, Chop, and Cpe. MIN6 β cells were untreated (CTL), treated with proinflammatory cytokines (Cyto) for 24 hours, or treated with thapsigargin (Tg) for 4 hours and then were subjected to PRP analysis with fractionation of the sedimentation gradient. A, Analysis of Atf4 mRNA in PRP fractions. B, Analysis of Chop mRNA in PRP fractions. C, Analysis of Cpe mRNA in PRP fractions. Representative data are shown on the left in A, B, and C, and quantitative data on the percentage of total mRNA residing in polyribosomes (fractions 6–10) are shown on the right. Data represent means ± SEM (n = 3–5). *, P < .05 compared with the control.