Table 2.

Cumulative excretion of radioactivity in urine, feces, and expired air as ¹⁴CO₂ after single oral administration of  ¹⁴C hyaluronic acid to rats (dose: 25 mg/kg).

Time (hr)	Excretion of radioactivity (% of dose)
	Urine	Feces	Expried air	Total
0–4	0.0 ± 0.0	—	1.5 ± 1.2	—
8	1.0 ± 0.3	—	45.9 ± 1.9	—
24	2.5 ± 0.3	7.8 ± 1.6	70.7 ± 1.2	81.1 ± 1.5
48	2.7 ± 0.2	11.0 ± 1.0	73.4 ± 1.3	87.0 ± 0.9
72	2.8 ± 0.2	11.4 ± 1.0	74.7 ± 1.5	88.8 ± 0.9
96	2.9 ± 0.2	11.6 ± 1.0	75.4 ± 1.5	89.9 ± 1.0
120	2.9 ± 0.2	11.7 ± 1.0	75.8 ± 1.5	90.4 ± 1.0
144	2.9 ± 0.3	11.8 ± 1.0	76.2 ± 1.5	90.9 ± 1.0
168	3.0 ± 0.2	11.9 ± 1.0	76.5 ± 1.6	91.3 ± 1.0
Carcass (168 hr)				8.8 ± 0.6

Data are expressed as the mean values ± S.D. of three animals.

—: not determined.