Table 1.
Results of the antifungal activities of the bulbs extract and its pure alkaloids
| Antifungal activities | |||
|---|---|---|---|
| experimental IC 50 (μg/mL) | endpoint IC 50 (μg/mL) | MIC (μg/mL) | |
| P. illyricum bulbs | 0.65 – 47 | 1.22 - 78 | 19.5 - 156 |
| Lycorine | 0.46 – 16.95 | 0.89 – 28.50 | 3.56 – 57 |
| Vittatine | - | - | - |
| Amphotericin B | 0.02 – 0.23 | 0.039 – 0.625 | 0.078 – 1.25 |
The following range concentrations were used in the microdilution broth methods: from 312 to 0.156 μg/mL for P. illyricum bulbs, from 114 to 0.03 μg/mL for lycorine; from 225 to 0.05 μg/mL for vittatine and from 5 to 0.002 μg/mL for amphotericin B.