Title |
1. Title |
Identification of the study as a systematic review, meta-analysis, or both |
Background |
2. Objectives |
The research question including components such as participants, interventions, comparators, and outcomes |
Methods |
3. Eligibility criteria |
Study and report characteristics used as criteria for inclusion |
4. Information sources |
Key databases searched and search dates |
5. Risk of bias |
Methods of assessing risk of bias |
Results |
6. Included studies |
Number and type of included studies and participants and relevant characteristics of studies |
7. Synthesis of results |
Results for main outcomes (benefits and harms), preferably indicating the number of studies and participants for each. If meta-analysis was done, include summary measures and confidence intervals. |
8. Description of the effect |
Direction of the effect (i.e., which group is favored) and size of the effect in terms meaningful to clinicians and patients |
Discussion |
9. Strengths and limitations of evidence |
Brief summary of strengths and limitations of evidence (e.g., inconsistency, imprecision, indirectness, or risk of bias, other supporting or conflicting evidence) |
10. Interpretation |
General interpretation of the results and important implications |
Other |
11. Funding |
Primary source of funding for the review |
12. Registration |
Registration number and registry name |