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. 2014 Oct 26;15:49. doi: 10.1186/s12865-014-0049-9

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© Goupil et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Cytokine production in supernatants of CD4+ T-cell subsets polarized in vitro . Naive CD4+ precursors were harvested from CD4C/HIV^MutA Tg and non-Tg mice, and incubated with (Th1, Th2, Th17, Treg) or without (control) subset-specific differentiating cytokines and blocking antibodies. *, significantly greater (p < 0.05) than the other subsets and control; **, significantly lower (P < 0.05) than the other subsets and control; ***, significantly lower (p < 0.05) than control. In all differentiating conditions, production of IL-1β and IL-6 was undetectable. Data are mean ± SD of 6 independent experiments.